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Powering Microbes with Electrons for Biomanufacturing

Sustainable production of valuable products

At a Glance

Researchers at Colorado State University have developed new ways to allow microbes to use electricity directly from electrodes. This approach makes it easier to guide microbes to produce useful fuels and chemicals. By improving how the electrodes are cleaned, designed, and monitored, the system produces more consistent results with fewer side products. These advances could lead to more reliable and efficient bio-based manufacturing via fermentation, anerobic digestion, and microbial electrosynthesis.

Background

Microbes naturally carry out chemical reactions, and with the right setup, electricity can give them extra energy to work faster or in new pathways. Instead of just using microbes to generate small amounts of electricity, scientists are now focusing on supplying them with electrical energy to make valuable products. Past attempts have been inconsistent because of problems like leftover films on electrodes, unstable conditions, and lack of proper controls. This new system overcomes those issues by combining better design and continuous monitoring of the electric field.

Overview

This technology improves how electricity is delivered from electrodes into microbes during fermentation, eliminating the need for a mediatior ion. It introduces reliable cleaning and preparation methods so electrodes don’t give false results, new reactor setups that make it easier to monitor and control electricity, and steady pH management to keep microbes healthy.

One key improvement is dynamic control, where the system automatically adjusts electricity levels based on real-time conditions. This avoids sudden changes that disrupt microbial activity and allows for more efficient production. Together, these improvements make experiments more accurate and set the stage for scaling up bio-electric fermentation for industry.

Benefits

  • Produces more reliable and repeatable results
  • Reduces errors caused by electrode buildup or side reactions
  • Keeps conditions steady for healthier microbial growth
  • Adjusts electricity levels automatically for efficiency
  • Works in both small test setups and larger systems

Applications

  • Making renewable fuels and bioplastics
  • Turning waste into energy or chemicals
  • Supporting carbon capture and reuse
  • Growing algae or microbes with added electrical energy
  • Manufacturing specialty chemicals in a sustainable way
Last Updated: November 2025
Close-up of branching glass tubes filled with green algae-like microbes, connected to electrical components, representing a system where electricity drives microbial growth and chemical production.
Opportunity

Available for Licensing
TRL: 3

IP Status

US Provisional Patent

Inventors

Ken Reardon
Danielle Bartholet
Claire Bailey

Reference Number
2025-039
Licensing Manager

Jessy McGowan
Jessy.McGowan@colostate.edu
970-491-7100

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