Organic Biopesticide for Control of Aphids

A Natural Insecticide: Cannabidvarinic Acid (CBDVA)

At a Glance

Researchers at Colorado State University have developed a potential biopesticide for the control of aphids, including the cannabis aphid. This can be utilized to organically control aphids and other biting/sucking insect pests in cannabis and hemp cultivation.


To date there has been little or no direction for insecticide use on Cannabis sativa by federal regulatory agencies. The number of insecticide products useful for pest management that are presently allowable for hemp production is quite limited. Essentially, these include various horticultural oils, some essential oils, insecticidal soaps, and a few botanically derived insecticides. The identification of an “organic” or natural biopesticide for use in the hemp industry will be of immense value to growers. Additionally, it is possible that CBDVA has potency to other pests of other crop species.


This technology involves the use of the cannabidivarinic acid (CBDVA), a known cannabinoid found in C. sativa, as a natural insecticide or biopesticide against pests like cannabis aphid. The research found that aphids had lower fecundity and survival on a diet supplemented with CBDVA, indicating its potential role in pest management.


  • Natural and organic, reducing the need for inorganic chemical pesticides.
  • Potential applicability to other crop pests, especially other biting/sucking insect pests.
  • Does not affect the cannabinoid levels in the plant.
  • Cost-effective and sustainable for growers.


  • Use in organic farming and sustainable agriculture approaches to insect and pest management.
  • Application in the cannabis/hemp industry for the control of pests where there are fewer current management options.
  • Potential development of new products for pest management in other crops.
Last Updated: April 2024

Available for Licensing
TRL: 6

IP Status

US Provisional Patent


Punya Nachappa

Jacob MacWilliams

Reference Number
Licensing Manager

Jessy McGowan