My group is interested in the molecular virology and biochemistry of mosquito-borne Arboviruses. Arboviruses, including flaviviruses and alphaviruses, are the most prevalent mosquito-borne viral pathogens worldwide. For example, approximately 2/3 of the world’s population is at risk for infection by dengue virus, yellow fever virus, West Nile virus, or related flaviviruses. Arbovirus infection can result in disease symptoms ranging from mild flu-like illness to debilitating encephalitis or death. Because arboviral infection is such a large health and socio-economic problem globally, my research has focused on finding ways to reduce human disease caused by these mosquito-borne viruses. We have a number of collaborative basic and translational research projects that involve flaviviruses (dengue, West Nile, and yellow fever) and alphaviruses (Sindbis, Chikungunya).
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